KMID : 1103720220830010246
|
|
Journal of the Korean Society of Radiology 2022 Volume.83 No. 1 p.246 ~ p.251
|
|
Breast Cancer after Radiation Therapy in a Patient with Li-Fraumeni Syndrome: A Case Report
|
|
Yoon In-Na
Cha Eun-Suk Kim Jeoung-Hyun Lee Jee-Eun Chung Jin
|
|
Abstract
|
|
|
Li-Fraumeni syndrome (LFS) is an inherited autosomal-dominant tumor-predisposition disorder caused by germline mutations in the TP53 tumor suppressor gene. Since patients with LFS are likely to develop therapy-related cancers, radiation therapy should be avoided if breast cancer is found in these individuals. Herein, we present a case of secondary breast cancer in an LFS patient after radiation and chemotherapy for the first diagnosed breast sarcoma.
|
|
KEYWORD
|
|
Breast Neoplasms, Li-Fraumeni Syndrome, Sarcoma, Second Primary
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|